Diffuse malignant pleural mesothelioma, or DMM, is a rare but highly aggressive type of cancer. It occurs in the thin layer of tissue, the pleura, lining the chest cavity and lungs. Once diagnosed with DMM, most patients do not survive beyond one year. This cancer is more common in men than in women, and in older people.
Most people with DMM have a history of exposure to asbestos; however, if they are not aware that such exposure occurred, they may be unaware that they are at risk. A patient with DMM typically has one or more of the following signs and symptoms: chest pain, shortness of breath, unexplained weight loss, fatigue, fever, or a cough. An x-ray usually shows that the pleural tissue around the lungs has thickened due to the development of a number of nodules or small cancerous growths. Sometimes, there may be a single large growth. When a biopsy of the cancer tissue is done, the types of cells that make up the cancer may be epithelioid, mixed, or sarcomatoid. People with epithelioid cell cancers tend to survive somewhat longer; those with sarcomatoid cancers usually have the shortest survival.
DMM is always treated as aggressively as possible. The type of treatment depends on the dominant cell type the cancer is made of, the extent of spread of the cancer, and the overall health of the person undergoing treatment. Surgery is a preferred option where the bulk of the cancer can be removed. Many anti-cancer drugs are being tried to treat DMM, with varying levels of short-term success. Radiotherapy may also be an option. A number of clinical trials are currently underway to try and find a treatment that may improve the outlook for DMM patients. However, only seven percent of people with DMM survive beyond five years.
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Malignant Pleural Mesothelioma Survival Rate
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Malignant pleural mesothelioma is the most common type of malignant mesothelioma. Many factors may be involved in determining the survival rate for this aggressive cancer; some are better understood than others. Estimates of median survival time range from one to two years; survival depends on...
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Malignant Mesothelioma Diagnosis
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When a patient has symptoms suggesting malignant mesothelioma, a doctor starts with imaging techniques to confirm a diagnosis. X-rays and CT scans of the chest or abdomen are taken to identify any abnormalities, such as fluid collections, thickening of tissue, or growths, that may indicate...
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Malignant Peritoneal Mesothelioma
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Malignant peritoneal mesothelioma is a cancer of the peritoneum, or tissue lining the abdomen and some of its organs. This lining tissue provides a small amount of lubricating fluid that allows organs in the gut to move and work properly. This cancer accounts for approximately...
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Malignant Diffuse Pleural Mesothelioma
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Majority of mesothelioma (cancerous tumor affecting mesothelial cells of organs) cases come under the classification ‘pleural mesothelioma’. This is a cancer that originates in the pleura, the delicate membrane covering the lungs. Out of these, seventy five percent are diffuse malignant pleural mesethelioma. The balance...
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Malignant Pleural Mesothelioma
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Malignant pleural mesothelioma is a cancer of the thin layer of tissue that lines the chest and lungs. It is a rare form of cancer that is mostly associated with exposure to asbestos. Malignant pleural mesothelioma is a fast-moving cancer with a median survival time...
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Malignant Mesothelioma Research
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Malignant mesotheliomas are highly aggressive cancers, usually linked to asbestos exposure. Most patients survive approximately one year after diagnosis, and only seven percent of patients make it past five years. If not diagnosed early, these cancers are extremely difficult to treat. However, early diagnosis is...
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A Guide To Malignant Mesothelioma
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Malignant mesothelioma is usually a fatal disease. Often by the time it is diagnosed, the cancer has spread extensively, even though the patient may not have had any earlier symptoms. Malignant mesothelioma affects about 2,000 people each year in the US. It is a fast-spreading...
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Malignant Mesothelioma
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Malignant mesothelioma is a rare cancer in which malignant or cancerous cells form in the thin layers of tissue lining the human chest, heart or abdomen. When the cancer is in the chest, it affects the pleura or tissue lining the lungs and is called...
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Pleural Mesothelioma Symptoms
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The earlier symptoms of malignant pleural mesothelioma are very similar to those experienced with other lung conditions, such as pneumonia or lung cancer. Symptoms also tend to present very gradually, and may therefore go unnoticed for a while. Breathlessness is one of the early and...
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Pleural Mesothelioma Information
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Pleural mesothelioma is the most common existing form of this malignancy, and it is more often than not a direct consequence of exposure to asbestos. One can get minor tumors with mesothelioma, but the malignant form is the most widespread. Inhaling asbestos fibers puts you...